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How much protein do you need on a GLP-1?

GLP-1 medications quiet your appetite, which is a big part of why they work. The catch: when you eat a lot less, protein usually drops too, and without enough protein your body is more likely to break down muscle along with fat. Protein is how you tell your body to hold on to it.
The daily target
A 2025 joint advisory from four major obesity and nutrition organizations suggests 1.2 to 1.6 grams of protein per kilogram of body weight per day during active weight loss. That is well above the standard 0.8 g/kg recommendation.
At Morphix, we keep it simple: about 0.7 grams per pound of your goal body weight. If your goal weight is 170 pounds, that is about 120 grams a day. If that math feels like too much, a flat 80 to 120 grams a day works for most people.
If you are over 50, or your appetite is very low, aim for the higher end. If you have kidney disease, do not use these numbers: get your target from your doctor.
Spread it out
Your body uses protein best in steady doses, not one big meal. Aim for:
- 3 to 4 eating times a day, each with 25 to 40 grams of protein.
- If that is too much food at once, try 5 smaller eating times of about 20 grams. A protein shake counts as one.
Three tricks for a small appetite
- Eat protein first. Start every plate with the protein, before the medication's fullness kicks in.
- Front-load your day. Appetite is usually better in the morning, so make breakfast your biggest protein meal.
- Drink some of it. Shakes, Greek yogurt smoothies and milk go down easier on nausea days.
What a day can look like
- Breakfast: 3 eggs plus egg whites and berries, about 30 g
- Lunch: grilled chicken salad with beans, about 35 g
- Snack: Greek yogurt or a protein shake, about 25 g
- Dinner: fish, vegetables and a half cup of rice, about 30 g
Protein alone is not enough
Protein gives your muscles the building blocks. Strength training gives them the reason to stay. You need both. Here is why lifting matters so much on a GLP-1.
Source: summary of the 2025 Joint Advisory (ACLM, ASN, OMA, TOS) and STEP 1 / SURMOUNT-1 body-composition results. This article is general education, not medical advice.